Have any Query? +91-80-41425832, 41525960 kop@kumarorganic.net

Antibacterial & Preservative Ingredients  

Kopcerin (Ethylhexylglycerin)

Kopcerin

Regulatory Status

      CAS-No: 70445-33-9

      INCI: Ethylhexylglycerin

      GHS SDS available

      Listed in DSL (Canada), ENCS(Japan), AICS/NICNAS, may be used in cosmetics in Europe (CIR expert panel report), TGA approved

    Certifications: GMP compliant, ISO Certified

Applications

  • Excellent moisturizer, controls microbial growth
  • Multi functional skin care additive

Efficacy Status

  • Acts as an antimicrobial stabilizer
  • It can boost the efficacy of traditional preservatives

Efficacy data

Test Organism Use of Concentration [%] Contact time [hours]
3h 6h 24h 48h 72h 168h
Escherichia coli(ATCC 8739) 0.0 C C C C C C
0.75
1.0
Pseudomonas aeruginosa (ATCC 9027) 0.0 C C C C C C
0.75
1.0
Candida albicans (ATCC10231) 0.0 C C C C C C
0.75 +
1.0
Aspergillus niger (16404) 0.0 C C C C C C
0.75 +++ ++ ++ +
1.0 ++ +
Symbol Findings Cfu/ml
No growth <100
+ Slight growth Approx. 102
++ Moderate growth Approx. 103
+++ Heavy growth Approx. 104
++++ Massive growth Approx. 105
C Surface covered >106

Kopsan (Triclosan)

kopsan

Regulatory Status

Certifications: GMP CERTIFIED, USFDA APPROVED
Reach: Pre Registered Under Reach

Applications

  • Used in deodorant which fights odor
  • Personal Hygiene (Skin Lotions, creams)
  • Used in Tooth paste, Oral products

Efficacy Status

  • Reduces skin flora on hands
  • Effective against gram-positive and gram- negative bacteria and against skin fungi
  • Stable to hydrolysis

Clinical data

kopsan_graph

Kopthonium (Benzethonium Chloride)


Benzethonium Chloride

Regulatory Status

Country

Status

Australia

Listed

Canada

DSL

EU

REACh None

Japan

Existing

USA

Listed

FDA permits Benzethonium Chloride to be used in OTC antimicrobial drug product intended to clean skin wounds

 Applications

Pharma-As an antimicrobial preservative in injections, ophthalmic and otic preparations

Cosmetics-Deodorant, Rash cream, foot odor powder, facial lotion, cleanser, make up and sun screen, mouth wash, and anti-itch ointment, anti bacterial moist hand wipes, antiseptic (first aid and cream), Sanitizers

Food Industry – Hard surface disinfectant

Efficacy Study 

Microorganism

MIC (mg/ml)

Aspergillus Niger

128

Candida Albicans

64

Escherichia Coli                                       

32

Penicillium Notatum                                 

64

Proteus Vulgaris

64

Pseudomonas Aeruginosa                        

250

Pseudomonas Cepacia                             

250

Pseudomonas Fluorescens                        

250

Staphylococcus Aureus                                

0.5

Streptococcus Pyogenes                       

0.5

Dosage in Formulation 

Pharma – 0.01% to 0.02% w/v

Cosmetic- Up to 0.5%

CIR (Cosmetic Ingredient Review) assessed this ingredient to be used safely up to 0.5% in OTC skin care products

Contact Us   

CONTACT INFO

  • Phone:+91-80-41425832, 41525960
  • Email id: kop@kumarorganic.net
  • Website: www.kumarorganic.net
  • Address: Kumar Organic Products Ltd, Usha Krishna Centre, NO. 819/C, 13th Cross, 7th Block (West), Near JSS College Circle, Jayanagar, Bangalore - 560082

Translate »