Biotech Centre

    Biocatalysis| Fermentation | Microbiology | Cell biology | Biochemistry | Bioinformatics | Molecular biology

    Fermentation

    In 2009, we embarked on the journey of fermentation-based products. This encompasses processes that leverage chemical changes initiated by living microorganisms, and our expertise extends across a wide range of production hosts, including bacteria, yeast, and fungi.

    BEST CHOICE

    Submerged Fermentation

    We have extensive experience in aerobic submerged fermentation processes, particularly in the production of secondary metabolites. Our expertise includes comprehensive control over pH, dissolved oxygen, temperature, stirring, foaming, and more, ensuring optimal productivity. Additionally, we excel in fed-batch fermentations, wherein extended and enhanced productivity can be achieved through the continuous or intermittent addition of one or more ingredients to the medium

    Solid State Fermentation

    We specialize in solid-state fermentation, a process that involves fermenting solid substrates with minimal water content, offering excellent economic feasibility. Its advantages include reduced energy demand, lower contamination risks, higher product yields, decreased water consumption, and ease of end-product recovery.

    Downstream Capabilities

    • Continuous Centrifugation
    • Microfiltration
    • Diafiltration
    • Ultrafiltration
    • Ion Exchange Resin Column Purification
    • Forced Circulation Evaporation
    • Agitated Nutsche Filtration Drying
    • Fluidized Bed Drying
    • Drum Drying

    Enzymatic Syntheses

    Our research expertise extends to enzymatic synthesis, leveraging natural catalysts like enzymes to drive chemical transformations in organic compounds. Specifically, we specialize in esterifications and trans esterifications, processes crucial for various industries including pharmaceuticals, cosmetics, and food. With a focus on sustainability and efficiency, we harness the power of enzymes to facilitate these reactions, resulting in high-quality products with minimal environmental impact.
    Through meticulous research and innovation, we continuously push the boundaries of enzymatic synthesis, unlocking new possibilities for our clients and contributing to the advancement of biotechnology.
    Advantages

    ❖ Green Technology
    ❖ Solvent free
    ❖ Mild conditions of reaction
    ❖ One - two steps reactions
    ❖ Renewable sources
    ❖ Zero discharge
    ❖ Recycle & reuse of enzymes
    ❖ Environment friendly

    Sustainable Extractions

    Harnessing Butylene Glycol for Green Solutions

    In our Green Extractions segment, we utilize Butylene Glycol sourced from fermentation as a sustainable solvent for extracting bioactive compounds from non-fermentable natural substrates. This approach not only ensures the efficient extraction of valuable compounds but also aligns with our commitment to sustainability and environmental responsibility. By opting for renewable and eco-friendly solvents, we minimize the environmental footprint of our extraction processes while maximizing the yield and quality of our extracted bioactive compounds.

    Efficacy Studies

    • Challenge Tests

    • Repeat Challenge Tests

    • Minimum Inhibitory Concentration

    • Zone of Inhibition

    • Residual Bacteriostatic Activity

    • Long-lasting Antimicrobial Effect

    • Germ Reduction Tests

    • Oral Biofilm Inhibition Studies

    • Contact Kill Assay

    • Rate Kill Assay

    • RBC Assay for Eye Irritation

    • Antityrosinase Assay

    • Anticollagenase Assay

    • Antielastase Assay

    • DPPH Assay

    • FRAP Assay

    • ABTS Radical Absorbance Capacity

    • Singlet Oxygen Absorbance Capacity

    • Superoxide Absorbance Assay

    • Nitric Oxide Absorbance Assay

    Cytotoxicity Assays/ Screening for Toxicity / Cell Viability Assay

    • MTT Assay

    • The Lactate Dehydrogenase (LDH) release Assay 

     

    Product Efficacy Testing

    • Wound Healing / Regeneration Assay

    • Estimation of Melanin Content/ Skin Lighting / Anti –  Melanogenic Assay

    QC Micro Biology

    We conduct comprehensive microbial limit tests on both raw materials and finished products, ensuring the highest standards of quality and safety. We perform rigorous water system validation and monitoring to guarantee the purity and integrity of our processes. Our environmental monitoring and area validation protocols ensure that our facilities maintain optimal conditions for production, adhering to strict regulatory requirements and industry best practices.

    Custom Research Projects

    The facility offers tailored R&D services to cosmeceutical, nutraceutical, and biotechnology companies with the utmost confidentiality and intellectual property protection. Whether it's developing a new process or enhancing an existing one, rest assured of our expertise

    Cost Effective Steps of Biosynthesis

    Process and Product Research and Development & Optimization

    Increasing Process Efficiency & Yield

    Replacing Environmentally Unsuitable