Ciclopirox Olamine is the olamine salt form of ciclopirox, a synthetic, broad-spectrum
antifungal agent with additional antibacterial and anti-inflammatory activities. It is used
primarily in the treatment of fungal infections of the skin and nails. It is available in various
formulations, including creams, gels, solutions, and nail lacquers. It is suitable for use in
both adults and children, although specific formulations and dosages may vary
depending on the age and condition being treated.
Its action is by binding to chelating trivalent cations, such as Fe3+ and Al3+, thereby
inhibiting the availability of essential co-factors for enzymes. In addition, ciclopirox exerts
its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).