Cetyl Pyridinium Chloride Monohydrate
Kopdinium Chloride
Cetylpyridinium chloride (CPC) is a quaternary ammonium compound, commonly used
as an antiseptic agent in various oral healthcare products, such as mouthwashes,
toothpaste, and throat lozenges. In oral care products, cetylpyridinium chloride
monohydrate is often included at concentrations ranging from 0.045% to 0.1% as an active
ingredient. It has broad-spectrum antimicrobial activity against both Gram-positive and
Gram-negative bacteria, as well as some fungi and viruses.
INCI Name
Cetylpyridinium chloride
Chemical Name
1-Hexadecylpyridin-1-ium chloride
Molecular weight
358.01 g/mol
CAS number
6004-24-6
EINECS number
204-593-9
Odour
Faint odor
Appearance
N/A
Solubility
Sparingly soluble in water but more soluble in organic
Application & Dosage
Cetylpyridinium chloride (CPC) is commonly found in mouthwashes, toothpaste, and
throat lozenges. These products, serve as an antiseptic agent to help reduce oral bacteria,
plaque formation, gingivitis, and bad breath. It may also be used in pharmaceutical
formulations for oral hygiene or throat infection. In mouthwash formulations, CPC
concentrations range from 0.045% to 0.1% (w/v) as an active ingredient. Users typically
rinse with the mouthwash for about 30 seconds to 1 minute before spitting it out.
Toothpaste; concentrations ranging from 0.05% to 0.15% (w/w). Throat Lozenges;
concentrations ranging from 1 mg to 4 mg per lozenge.
Stability & Storage Store CPC in tightly sealed containers at room temperature (typically between 20°C to 25°C or 68°F to 77°F). Avoid exposure to extreme temperatures. CPC may be sensitive to extreme pH levels, so it’ s advisable to avoid highly acidic or alkaline environments during storage.
Stability & Storage Store CPC in tightly sealed containers at room temperature (typically between 20°C to 25°C or 68°F to 77°F). Avoid exposure to extreme temperatures. CPC may be sensitive to extreme pH levels, so it’ s advisable to avoid highly acidic or alkaline environments during storage.